Evaluation of the Presence of Enthesitis in Patients With Acne Vulgaris
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- patellar tendon thicknesses of patients with acne vulgaris and healthy controls
研究概览
简要总结
Acne vulgaris is an inflammatory disease of the pilosebaceous unit, affecting about 85% of the young population. In the studies p. acne is a potent stimulator of the release of IFN-gamma (IFN-)) and IL-17 from CD4 + T cells, and the presence of IL-17 + cells in the perifollicular infiltrate has been shown in biopsies of inflammatory acne lesions. Therefore, acne is thought to be a Th17-related disease (1).
This study was aimed to evaluate the presence of enthesitis in patients with acne vulgaris.
详细描述
Patients with acne vulgaris and healthy controls aged between 18-25 who admitted to Hitit University Erol Olcok Education and Research Hostpital Dermatology policlinic will be icluded. Patients with rheumatic, neurological diseases, history of trauma and previous fractures will be excluded from the study. After all the participants were evaluated by the dermatologist and demographic data will be recorded, the participants will be examined by the physical medicine and rehabilitation specialist and the short form-36 (sf-36), hospital anxiety and depression scale will be completed. Bilateral lower extremity tendon thicknesses and the presence of erosion, bursitis, etc. will be evaluated according to the criteria of Guess (Glasgow Ultrasound Enthesitis Scoring System) and Guess score will be determined for all participants. A total of 48 participants, 24 patients with acne vulgaris and 24 healthy controls, will be included in the study (2).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 25 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Participants with rheumatic and neurologic disease, history of trauma ,
结局指标
主要结局
patellar tendon thicknesses of patients with acne vulgaris and healthy controls
时间窗: 3 months
Ashilles tendon thicknesses of patients with acne vulgaris and healthy controls
时间窗: 3 months
次要结局
未报告次要终点
研究者
Dilek Eker Büyükşireci
Specialist doctor
Erol Olcok Corum Training and Research Hospital
