A Cross-sectional Study - The Quality of Life in Individuals With Parkinson's Disease: Is it Related to Functionality and Tremor Severity?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Parkinson's Disease Quality of Life Questionnaire (PDQ-39)
研究概览
简要总结
This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. The differences between Parkinson's Disease Quality of Life Questionnaire, Nine-Hole Peg Test, grip and pinch strength values in the individuals with and without tremor in the study were investigated.
详细描述
Evaluating the relationship between Quality of Life and tremor is needed to determine the best physiotherapy and rehabilitation approaches for individuals with Parkinson's Disease. This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. Fifty-two individuals with Parkinson's Disease participated in the study. Quality of Life, tremor amplitude, upper limb functionality, grip and pinch strength were evaluated. The relationship of quality of life with tremor severity and upper limb functionality was examined in individuals with Parkinson's Disease. The results of individuals with and without tremor were compared.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Definite diagnosis of idiopathic Parkinson Disease
- •Age between 40 and 80 years
- •Being literate
- •Having a grade between 1-4 from the Modified Hoehn and Yahr Scale
- •Having a score lower than 11 in Hospital Anxiety and Depression Scale
排除标准
- •Who were with any other neurologic or orthopedic or rheumatologic disease affecting the upper extremity
- •Using antidepressants
- •Having vision loss
- •Deep brain stimulation
结局指标
主要结局
Parkinson's Disease Quality of Life Questionnaire (PDQ-39)
时间窗: 1 year
Used to assess the quality of life of Parkinson's patients
Nine-Hole Peg Test
时间窗: 1 year
Used to assess the upper limb functionality of Parkinson's patients
Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale
时间窗: 1 year
The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale. Used for the evaluation of clinical manifestations of Parkinson's disease. The scale consists of 4 subscales: the first part is Non-Motor Aspects of Experiences of Daily Living (13), the second part is Motor Aspects of Experiences of Daily Living (13), the third part is Motor Examination (33), and the fourth part is Motor Complications (6). The total number of items in the scale is 65. The minimum score is 0. The maximum MDS-UPDRS score is higher, given the additional items and scores for each body area, with a maximum score of 272. Higher scores indicate greater impact of Parkinson Disease symptoms.
Hospital Anxiety and Depression Scale
时间窗: 1 year
The Hospital Anxiety and Depression Scale aims to measure symptoms of anxiety and depression and consists of 14 items, seven items for the anxiety subscale (Hospital Anxiety and Depression Scale Anxiety) and seven for the depression subscale (Hospital Anxiety and Depression Scale Depression). Each item is scored on a response-scale with four alternatives ranging between 0 and 3. After adjusting for six items that are reversed scored, all responses are summed to obtain the two subscales. Both depression and anxiety subheadings are scored between 0 and 21. Higher scores indicate greater levels of anxiety or depression. Cut-off scores are 8-10 for doubtful cases and ≥11 for definite cases.
Dynamometer
时间窗: 1 year
Used to assess the grip and pinch strength of Parkinson's patients
Electromyography
时间窗: 1 year
Used to assess the tremor amplitude of Parkinson's patients
次要结局
未报告次要终点
研究者
Buse KILINÇ
PT.MSc.
Pamukkale University