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The Quality of Life in Individuals With Parkinson's Disease

Completed
Conditions
Parkinson Disease
Functionality
Tremor
Registration Number
NCT05906693
Lead Sponsor
Pamukkale University
Brief Summary

This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. The differences between Parkinson's Disease Quality of Life Questionnaire, Nine-Hole Peg Test, grip and pinch strength values in the individuals with and without tremor in the study were investigated.

Detailed Description

Evaluating the relationship between Quality of Life and tremor is needed to determine the best physiotherapy and rehabilitation approaches for individuals with Parkinson's Disease. This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. Fifty-two individuals with Parkinson's Disease participated in the study. Quality of Life, tremor amplitude, upper limb functionality, grip and pinch strength were evaluated. The relationship of quality of life with tremor severity and upper limb functionality was examined in individuals with Parkinson's Disease. The results of individuals with and without tremor were compared.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
52
Inclusion Criteria
  • Definite diagnosis of idiopathic Parkinson Disease
  • Age between 40 and 80 years
  • Being literate
  • Having a grade between 1-4 from the Modified Hoehn and Yahr Scale
  • Having a score lower than 11 in Hospital Anxiety and Depression Scale
Exclusion Criteria
  • Who were with any other neurologic or orthopedic or rheumatologic disease affecting the upper extremity
  • Using antidepressants
  • Having vision loss
  • Deep brain stimulation

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Nine-Hole Peg Test1 year

Used to assess the upper limb functionality of Parkinson's patients

Parkinson's Disease Quality of Life Questionnaire (PDQ-39)1 year

Used to assess the quality of life of Parkinson's patients

Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale1 year

The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale. Used for the evaluation of clinical manifestations of Parkinson's disease. The scale consists of 4 subscales: the first part is Non-Motor Aspects of Experiences of Daily Living (13), the second part is Motor Aspects of Experiences of Daily Living (13), the third part is Motor Examination (33), and the fourth part is Motor Complications (6). The total number of items in the scale is 65. The minimum score is 0. The maximum MDS-UPDRS score is higher, given the additional items and scores for each body area, with a maximum score of 272. Higher scores indicate greater impact of Parkinson Disease symptoms.

Hospital Anxiety and Depression Scale1 year

The Hospital Anxiety and Depression Scale aims to measure symptoms of anxiety and depression and consists of 14 items, seven items for the anxiety subscale (Hospital Anxiety and Depression Scale Anxiety) and seven for the depression subscale (Hospital Anxiety and Depression Scale Depression). Each item is scored on a response-scale with four alternatives ranging between 0 and 3. After adjusting for six items that are reversed scored, all responses are summed to obtain the two subscales. Both depression and anxiety subheadings are scored between 0 and 21. Higher scores indicate greater levels of anxiety or depression. Cut-off scores are 8-10 for doubtful cases and ≥11 for definite cases.

Dynamometer1 year

Used to assess the grip and pinch strength of Parkinson's patients

Electromyography1 year

Used to assess the tremor amplitude of Parkinson's patients

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Pamukkale University

🇹🇷

Denizli, Pamukkale, Turkey

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