Comparing the efficacy of low-level light laser therapy plus minoxidil 5% and minoxidil 5% alone in the treatment of androgenetic alopecia
- Conditions
- Androgenetic alopecia.Androgenic alopecia
- Registration Number
- IRCT2016022726780N1
- Lead Sponsor
- Vice Chancellor for Research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
consent to participate; absence of other causes of hair loss; types 1-4 on Fitzpatrick scale; stages 3-6 on Norwood Hamilton Scale (for male patter baldness); stages 2-3 on the Ludwig Scale for hair loss in women; no history of finasteride, antiandrogens (e.g. cyproterone, spironolactone, ketoconazole, and flutamide), topical estrogen, progesterone, tamoxifen, anabolic steroids, drugs potentially associated with hypertrichosis (e.g. cyclosporine, diazoxide, phenytoin, oral glucocorticoids, lithium, and phenothiazine during the three-month period before the study.
Exclusion criteria: using the above-mentioned medicines during the study; lack of adherence to treatment protocol; hair transplant; any medical conditions leading to hair loss (e.g. HIV/AIDS, connective tissue disease, and inflammatory bowel disease); development of endocrinopathies such as PCO, ovarian and adrenal gland tumors, and hypothyroidism.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hair density. Timepoint: Before the intervention, 3, 6, 9, and 12 months after the intervention. Method of measurement: Phototrichogram.;Hair shaft diameter. Timepoint: Before the intervention, 3, 6, 9, and 12 months after the intervention. Method of measurement: Phototrichogram.;Patient satisfaction. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Questionnaire.;Hair regrowth based on patient's opinion. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Visual analog scale.;Hair regrowth based on physician's opinion. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Digital image and observation.
- Secondary Outcome Measures
Name Time Method Headache. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Asking patients.;Erythema. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Asking patients.;Itching. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Asking patients.;Hypopigmentation. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Observation and asking patients.;Hyperpigmentation. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Observation and asking patients.