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Clinical Trials/NCT00724555
NCT00724555
Completed
Not Applicable

Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities

Georgetown University8 sites in 1 country2,005 target enrollmentFebruary 2008
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Georgetown University
Enrollment
2005
Locations
8
Primary Endpoint
The proportion of people with ischemic stroke appropriately treated with IV tPA.
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The purpose of this study is to increase treatment of acute stroke with tissue plasminogen activator (tPA) across the District of Columbia. This study, however, will not evaluate tPA as an intervention.

Detailed Description

There are a number of well-known barriers to receiving tissue plasminogen activator (tPA) including transit time to hospital, paramedic and provider training, tPA standing orders, and provider guidelines. Among underserved populations, limited stroke knowledge, socioculturally determined attitudes, and beliefs and myths held by community members may serve as additional barriers that hinder these populations from receiving tPA and acute stroke care. Targeted multilevel interventions designed to overcome specific barriers may significantly increase the number of individuals with stroke who are appropriately treated with intravenous tPA (IV tPA) in underserved communities. Identification of the specific components of healthcare interventions that are the most effective is critical to improve delivery of acute stroke therapy. The goal of this study is to learn more about public knowledge, attitudes, beliefs and perceptions regarding stroke and stroke treatment in order to identify sociocultural and environmental barriers to receiving tPA and acute stroke care in an underserved community. This study will also determine if implementation of a multilevel intervention program can significantly increase the number of people with ischemic stroke who are appropriately treated with IV tPA in a predominantly underserved community. In the study, researchers will evaluate the different levels of the intervention to determine which efforts are most effective.

Registry
clinicaltrials.gov
Start Date
February 2008
End Date
January 2013
Last Updated
12 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Chelsea Kidwell, M.D.

Professor of Neurology and Medical Director, Georgetown University Stroke Center

Georgetown University

Eligibility Criteria

Inclusion Criteria

  • diagnosis of acute ischemic stroke
  • over the age of 18

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

The proportion of people with ischemic stroke appropriately treated with IV tPA.

Time Frame: 4 years

Secondary Outcomes

  • Qualitative data collected from the community will identify baseline levels of knowledge, attitudes, and perceived and encountered barriers to acute stroke treatment.(1 year)

Study Sites (8)

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