To examine changes in neurocognitive functions after cranial radiation therapy.
Not Applicable
- Conditions
- Health Condition 1: C349- Malignant neoplasm of unspecifiedpart of bronchus or lung
- Registration Number
- CTRI/2019/10/021511
- Lead Sponsor
- Tata Memorial Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Pathologically proven diagnosis of NSCLC
Age more than or equal to 18 years
Karnofsky Performance status more than 70
Exclusion Criteria
Prior radiosurgery, whole brain radiotherapy, or cranial radiotherapy
Previous surgical resection of brain metastasis (biopsy is allowed)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare neurocognitive function as measured by neurocognitive decline on a Hopkins Verbal Learning Test-Revised (HVLT-R) for Total Recall, delayed recall and delayed recognition from baseline to 3 monthsTimepoint: 3 months
- Secondary Outcome Measures
Name Time Method 1.To compare neurocognitive function using different neurocognitive battery tests from baseline to 3,6, 9 and 12 monthsTimepoint: 3,6, 9 ad 12 months