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Clinical Trials/NCT05356091
NCT05356091
Completed
Not Applicable

Comparison of Postoperative Recovery Quality Between Sevoflurane and Remimazolam for General Anesthesia for Transurethral Resection of Bladder Tumor

Kangbuk Samsung Hospital1 site in 1 country36 target enrollmentDecember 2, 2022

Overview

Phase
Not Applicable
Intervention
Sevoflurane
Conditions
Quality of Recovery
Sponsor
Kangbuk Samsung Hospital
Enrollment
36
Locations
1
Primary Endpoint
Quality of recovery -15 score at postoperative day 1
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

This study was designated to investigate the quality of recovery after transurethral bladder resection. Because, patients undergoing transurethral bladder resection are mostly old age, and because of catheter-related bladder discomfort are common after transurethral bladder resection, study on the quality of recovery after transurethral bladder resection seems to be meaningful. In general, sevoflurane is commonly used as an anesthetic agent for general anesthesia of transurethral bladder resection. The purpose of this study is to investigate whether remimazolam is not inferior to sevoflurnane in terms of quality of recovery after transurethral bladder resection.

Registry
clinicaltrials.gov
Start Date
December 2, 2022
End Date
February 24, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Kangbuk Samsung Hospital
Responsible Party
Principal Investigator
Principal Investigator

Eunah Cho, MD

Assistant Professor

Kangbuk Samsung Hospital

Eligibility Criteria

Inclusion Criteria

  • adult patients aged from 19 years
  • Americaln Society of Anesthesiologist's class I, II, and III
  • scheduled to undergo elective transurethral bladder resection under general anesthesia

Exclusion Criteria

  • refuse to participate in the study
  • cannot read, or sign the consent form (e.g., iliterate, foreigner, eye disease)
  • history of allergy to benzodiazepines
  • decreased liver, kidney, or heart function
  • pregnant women or breastfeeding patients
  • history of drug or alcohol abuse
  • obesity (body mass index \> 30kg/m2)

Arms & Interventions

Sevoflurane

General anesthesia using sevoflurane

Intervention: Sevoflurane

Remimazolam

General anesthesia using remimazolam

Intervention: Remimazolam

Outcomes

Primary Outcomes

Quality of recovery -15 score at postoperative day 1

Time Frame: postoperative day 1

Quality of recovery-15 questionnaire, which consists 15 questions. The score ranges from 0 to 150. The higher the score, the better the quality of recovery.

Secondary Outcomes

  • Catheter related bladder discomfort(5 minutes, and 1 hour after post-anesthesia circuit unit arrival.)

Study Sites (1)

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