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Clinical Trials/NCT00406744
NCT00406744
Terminated
Phase 3

Evaluation of Efficacy of Intravitreal Bevacizumab Retreatments

Asociación para Evitar la Ceguera en México1 site in 1 country20 target enrollmentMay 2006
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ConditionsAge Related Macular DegenerationChoroidal Neovascularization
DrugsIntravitreal injection of Bevacizumab

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Age Related Macular Degeneration
Sponsor
Asociación para Evitar la Ceguera en México
Enrollment
20
Locations
1
Primary Endpoint
Best corrected visual acuity, OCT foveal thickness and fluorescein angiogram
Status
Terminated
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Choroidal neovascularization is a leading cause of visual loss in people older than 60 years and for its treatment there had been performed multicentric studies with Lucentis (Ranibizumab) with a significant improval of visual acuity. In our institution we evaluated efficacy of bevacizumab in several pathologies but we dont know what would be the results if we use the same dose several times. Our purpose was to determine the efficacy of bevacizumab for improve or stabilize visual acuity with two or more intravitreal inyections of bevacizumab.

Registry
clinicaltrials.gov
Start Date
May 2006
End Date
November 2006
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Asociación para Evitar la Ceguera en México

Eligibility Criteria

Inclusion Criteria

  • •\* Any visual acuity
  • •OCT: Central foveal thickness greater than 300 u or with evidence of subretinal fluid.
  • •Active angiogram leakage

Exclusion Criteria

  • •\* Basal Inflammatory disease
  • •Endoftalmitis history
  • •Lesions bigger than 5400 u or with scarring greater than 50% of lesion.

Outcomes

Primary Outcomes

Best corrected visual acuity, OCT foveal thickness and fluorescein angiogram

Study Sites (1)

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