NCT00406744终止3 期
Evaluation of Efficacy of Intravitreal Bevacizumab Retreatments
Asociación para Evitar la Ceguera en México2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2006年5月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 终止
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Best corrected visual acuity, OCT foveal thickness and fluorescein angiogram
研究概览
简要总结
Choroidal neovascularization is a leading cause of visual loss in people older than 60 years and for its treatment there had been performed multicentric studies with Lucentis (Ranibizumab) with a significant improval of visual acuity. In our institution we evaluated efficacy of bevacizumab in several pathologies but we dont know what would be the results if we use the same dose several times. Our purpose was to determine the efficacy of bevacizumab for improve or stabilize visual acuity with two or more intravitreal inyections of bevacizumab.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •* Any visual acuity
- •OCT: Central foveal thickness greater than 300 u or with evidence of subretinal fluid.
- •Active angiogram leakage
排除标准
- •* Basal Inflammatory disease
- •Endoftalmitis history
- •Lesions bigger than 5400 u or with scarring greater than 50% of lesion.
结局指标
主要结局
Best corrected visual acuity, OCT foveal thickness and fluorescein angiogram
次要结局
未报告次要终点
研究者
研究点 (2)
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