The Effects of Over-the-Counter Products on the Skin
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Photoaging
研究概览
简要总结
The primary purpose of this study is to investigate the safety and tolerability of commonly used over-the-counter products and the effects of the products on skin health.
详细描述
Participant will apply commonly used skin product on skin for a period of time with or without light challenge. The investigators will perform clinical assessments of the skin associated with product application as well as assess these changes with and without light challenge. Skin biopsies will be obtained following standard medical practice and will be used to analyze skin markers related to photoaging, pigmentation, oxidative stress, and other dermatologic conditions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participants must be over the age of 18 years old with healthy skin;
- •Participant must be willing and comply with the requirements of the protocol;
- •Participant must have the ability to understand and communicate with the investigator;
- •Participant must provide informed consent.
排除标准
- •Subjects who are unable to provide informed consent;
- •Subject with significant medical history or current skin diseases that the investigator feels is not safe for study participation;
- •Subjects who self-report that they are pregnant or nursing;
- •Subjects who do not speak English or have difficulty hearing or are otherwise impaired for providing informed consent and communicating with the investigator;
- •Subjects with known bleeding disorders or diathesis;
- •Subjects with a history of keloids or excessive scarring;
- •Subjects with known allergy to lidocaine, epinephrine, or any of the tested products;
- •Subjects who foresee intensive UV exposure during the study (e.g. sunbathing, tanning beds).
结局指标
主要结局
Photoaging
时间窗: 1 year
This will be assessed using the Griffiths Photoaging Photonumeric scale with range from 1 to 10 with increasing numbers representing advanced photoaging
次要结局
未报告次要终点