European Quality Improvement Programme for Acute Coronary Syndromes

Not Applicable

• Conditions: Acute Coronary Syndrome

• Registration Number: NCT00716430
• Lead Sponsor: Royal Brompton & Harefield NHS Foundation Trust

Brief Summary

The main hypothesis to be tested is that the use of a quality improvement programme will lead to measurable improvements in the management of care and use of evidence based treatments for patients presenting to hospital with non-ST elevation acute coronary syndromes.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08
• Status Verified: 2008-07
• Study First Submitted: 2008-07-11
• Study First Submitted QC: 2008-07-15
• Last Update Submitted: 2008-07-15
• Study First Posted: 2008-07-16
• Last Update Posted: 2008-07-16
• Primary Completion: 2008-12
• Study Completion: 2009-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 3500

Inclusion Criteria

Patients with a good clinical history of ACS and at least one of the following:

• New or transient ST or T wave changes on the ECG consistent with acute myocardial ischaemia
• Elevation of troponin or other cardiac markers to levels indicative of myocardial necrosis according to local laboratory values

Exclusion Criteria

• Evidence of persistent ST elevation on the ECG
• Use of early reperfusion therapy
• Patients >80 years
• Patients transferred from another hospital

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Composite of 7 outcome measures to assess aggregate potential for improvement in care using the QI programme:1:risk stratification within 24 hrs, 2:early coronary angiography, 3:anticoagulation, 4:beta-blockers, 5:statins, 6:ACE-inhibitors, 7:Clopidogrel	10 months

Secondary Outcome Measures

Name	Time	Method
Clinical outcomes at discharge including death and myocardial infarction	10 months
Estimated costs of care for patients	10 months
Estimated costs and economic evaluation of potential cost-effectiveness of QI programme	10 months

Trial Locations

Locations (37)

Centre Hospitalier de la region d'Annecy; 🇫🇷 Annecy, France

Centre Hospitalier de Chambery; 🇫🇷 Chambery, France

Cardiology dept. B, CHU Hopital G. Montpied; 🇫🇷 Clermont Ferrand, France

CHU de Grenoble; 🇫🇷 Grenoble, France

Centre Hospitalier de Riom Guy Thomas; 🇫🇷 Riom, France

Hopitaux Drome Nord de Romans-sur-Isere; 🇫🇷 Romans-sur-Isere, France

Centre Hospitalier d'Ussel; 🇫🇷 Ussel, France

Centre Hospitalier Pierre Bazin; 🇫🇷 Voiron, France

Ospedale M. Bufalini; 🇮🇹 Cesena, Italy

Ospedale Morgagni-Pierantoni; 🇮🇹 Forli, Italy

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