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Dismantling the Components and Dosing of CBT for Co-Occurring Disorders

Not Applicable
Completed
Conditions
CBT Decoupling
CBT Anxiety Reduction
CBT Combined
Registration Number
NCT02161211
Lead Sponsor
University of Minnesota
Brief Summary

The purpose of this study is to establish a brief CBT intervention that can largely, if not fully eliminate the deleterious effect of common co-occurring anxiety disorders on alcohol use disorder treatment outcomes.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
300
Inclusion Criteria
  • diagnostic and Statistical Manual IV diagnosis of panic disorder, generalized anxiety disorder, and/or social anxiety disorder within the past 30 days;
  • inpatient treatment at Lodging Plus primarily for alcohol (vs. other drug) dependence
  • alcohol use in the 30 days preceding the study
  • ability to provide informed consent
  • minimum of a sixth grade reading level (deemed necessary to complete study materials);
  • willingness to provide contact information to confirm study follow-up appointments
  • lives within proximity to the Twin Cities (e.g., within about an hour's drive) for the purpose attending follow-up visits
Exclusion Criteria
  • lifetime history of psychosis or mania by history
  • cognitive or physical impairment that precludes study participation
  • currently and seriously suicidal (i.e., plan and intent)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Number of Participants That Relapsed to Drinking at 4 Months4 month follow-up

Relapse status will be assessed using categorical relapse status (yes vs. no). Count is of those who relapsed

Number of Drinking Days in 4 Months Post Treatment4-months

Negative binomial regression with offset for possible drinking days exposure in 4 months post treatment

Number of Standard Drinks Per Drinking Day4 months

Drinks per drinking day among those who relapsed by 4 months. Standard Drink is defined as 12oz beer, 4ox wine, 3oz fortified wine, 1oz hard liquor

Secondary Outcome Measures
NameTimeMethod
Number of Participants Who Met SCID-IV Criteria for Alcohol Dependence at 4 Months4 months

Relapse to Diagnostic and Statistical Manual (DSM)-IV alcohol dependence criteria based on Structured Clinical Interview for DSM-IV (SCID) at 4 months

Number of Participants Who Relapsed to Hazardous Drinking4 months

Relapse to hazardous drinking (hazardous drinking is defined as 3 or more per occasion for women or more than 7 drinks per week, 4 or more per occasion for men or more than 14 drinks per week) at 4 months

Trial Locations

Locations (1)

Lodging Plus Program, Fairview Hospital

🇺🇸

Minneapolis, Minnesota, United States

Lodging Plus Program, Fairview Hospital
🇺🇸Minneapolis, Minnesota, United States

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