Does COVİD-19 m-RNA Vaccine Affect Fertility and Over Reserve ?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Ovarian reserve tests and fertility status of 74 women before and after vaccination
研究概览
简要总结
Women's ovarian reserve and fertility were compared before and after 2 doses of vaccination
详细描述
our study ıs desıgned as an observatıonal clınıcal study. the purpose ıs to compare the over reserve tests of the patıents before and after vaccıne, to determıne ıf the over reserve and fertılıty of women are affected by the vaccıne.women who applied to the vaccination outpatient clinic for the first dose of vaccine were included in the study.those who have never been vaccinated and have not had covid 19 infection were included in the study.antı ullerıan hormone level ıs the laboratory parameters that best showıng the ovary reserve today. ovarian reserve tests including amh were checked and their fertility was questioned and their information was recorded.
the same tests were repeated after the volunteers received 2 doses of vaccine. ın the power analysis, it was calculated that 104 volunteers should be included in the study.the study will be terminated when 104 volunteers are reached.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •between 18-45 years old
- •have ever had a covid vaccine
- •not be infected with covid 19
排除标准
- •pregnancy
- •diagnosis of any kind of cancer
- •oral contraceptive usage
- •endometrioma
- •menopause
- •menstrual irregularity
- •premature ovarian insufficiency
结局指标
主要结局
Ovarian reserve tests and fertility status of 74 women before and after vaccination
时间窗: 6 months after receiving the 2nd dose of vaccine
before and after vaccination serum Amh level ng/ml
次要结局
- AMH difference between vaccinated and unvaccinated groups(6 months)
研究者
Elif Yıldız
DOCTOR
Gaziosmanpasa Research and Education Hospital