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临床试验/CTRI/2023/03/050856
CTRI/2023/03/050856已完成不适用

Efficacy of Pre-operative submucosal injection of Dexamethasone And Triamcinolone Acetonide on Post-Operative Pain following endodontic treatment of teeth with Irreversible Pulpitis: A Randomized Clinical Trial

DR PARI ANAND1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2023年3月22日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
post operative pain using Heft-Parker visual analogue scale (HP VAS)

研究概览

简要总结

The aim of the study was to evaluate the effects of submucosal single doses of dexamethasone and triamcinolone acetonide on postoperative pain after single visit root canal treatment of teeth with symptomatic irreversible pulpitis. Thirty patients were selected and allocated in three groups. Group I  received saline (control), Group II  received dexamethasone (8mg) and Group III  received triamcinolone acetonide (40mg) before endodontic treatment is initiated. Root canal treatment was performed in a single appointment for all the participants. Post-operative pain was assessed using Heft-Parker visual analogue scale (HP VAS). The results showed that Preoperative doses of corticosteroids resulted in adecrease of post endodontic pain following single visit root canal treatment ofteeth with symptomatic irreversible pulpitis

研究设计

研究类型
Interventional
分配方式
Stratified randomization
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • •Healthy adults aged 18-50 years of age with symptomatic irreversible pulpitis.
  • •Patients with good general health and no chronic systemic diseases.
  • •Patients with a radiographically normal periapical region.

排除标准

  • •Teeth with periapical pathology, abscess, calcified canals or aberrant anatomy.
  • •Patients with History of allergy to Local anesthesia or any other experimental drugs.
  • •Patients with systemic disorders, pregnant and breastfeeding mothers and any conditions that contradict use of steroids.
  • •Patients with use of analgesics or anti-inflammatory drugs 12 hours prior to the procedure.

结局指标

主要结局

post operative pain using Heft-Parker visual analogue scale (HP VAS)

时间窗: PRE-OP, POST-OP AFTER 6HRS, 12HRS, 24HRS,48HRS AND 72 HRS.

次要结局

  • POST OPERATIVE PAIN USING Heft-Parker visual analogue scale (HP VAS)(PRE-OP,POST-OP AFTER 6HRS, 12HRS,24HRS,48HRS, 72 HRS)

研究者

发起方
DR PARI ANAND
申办方类型
Other [individual]

研究点 (1)

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