Tenecteplase for acute ischemic stroke with large vessel occlusio
- Conditions
- Acute ischemic strokeIschemic stroke, thrombolysis, tenecteplase, alteplase, recanalization
- Registration Number
- JPRN-jRCTs051210055
- Lead Sponsor
- Toyoda Kazunori
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 220
1. Patients presenting with acute ischemic stroke
2. 20 years and over
3. Male or female
4. Eligible to commence intravenous thrombolysis within 4.5 hours of stroke onset
5. Arterial occlusion on CTA or MRA of ICA, M1, M2, or basilar artery
6. Eligible to commence mechanical thrombectomy (arterial puncture) within 6 hours of stroke onset
7. Written informed consent is obtained from patient or proxies
1. Pre-stroke mRS score 4 or more
2. More than 4.5 hours of stroke onset or last known well time
3. Contraindication to contrast agents
4. Any terminal illness that the patient would not be expected to survive more than 1 year
5. Breast-feeding or possibly pregnant
6. Patients who are participating or plan to participate in other clinical trials during this trial period
7. Considered ineligible for trial enrollment by the investigators
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method