Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia

Not Applicable

Completed

• Conditions: Fanconi's Anemia; Myelodysplastic Syndromes; Leukemia, Nonlymphocytic, Acute; Leukemia, Lymphocytic, Acute

• Registration Number: NCT00005892
• Lead Sponsor: Fairview University Medical Center

Brief Summary

OBJECTIVES:

I. Determine the effectiveness of moderate dose cyclophosphamide and radiotherapy in terms of improving survival and reducing the morbidity following allogeneic bone marrow transplantation in patients with myelodysplastic syndrome and acute leukemia related to Fanconi's anemia.

Detailed Description

PROTOCOL OUTLINE:

Patients receive cyclophosphamide IV over 1-2 hours on day -6 through -3 and total body radiotherapy on day -1. Patients undergo allogeneic bone marrow transplantation on day 0.

Study Timeline

• Study Start: 2000-03
• Study First Submitted: 2000-06-02
• Study First Submitted QC: 2000-06-02
• Study First Posted: 2000-06-05
• Status Verified: 2004-07
• Last Update Submitted: 2005-06-23
• Last Update Posted: 2005-06-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Fairview University Medical Center; 🇺🇸 Minneapolis, Minnesota, United States