Comparison of Hepatitis B surface Antibody levels after vaccination with combined one dose hexavalent-based vaccine (DTaP-IPV-HB-Hib) with two doses of pentavalent-based vaccine (DTwP-HB-Hib) versus three doses of pentavalent-based vaccine (DTwP-HB-Hib)
Phase 4
Completed
- Conditions
- PCV pneumococcal conjugated vaccineThe anti-HBs antibody levels after vaccination with combined one dose hexavalent-based vaccine (DTaP-IPV-HB-Hib) with two doses of pentavalent-based vaccine (DTwP-HB-Hib) versus three doses of pentavalent-based vaccine (DTwP-HB-Hib) at 3-6 months after the last dose of vaccination.HBV hepatitis B virusGMT geometric mean
- Registration Number
- TCTR20240513002
- Lead Sponsor
- Research center, Faculty of Medicine Ramathibodi Hospital, Mahidol University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 76
Inclusion Criteria
Infants who born at a gestational age more than 36 weeks
Infants aged 30 to120 days who received a monovalent HBV vaccine at birth
Exclusion Criteria
Infants not born to HIV- or HBV-infected mothers and those with coagulopathy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anti-HBs level 3-6 months after the last dose of vaccination Blood sampling for anti-HBs level
- Secondary Outcome Measures
Name Time Method Compare adverse events 7 day after each vaccination Reported by phone for gathering information