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Tryptophan and Behavior Therapy for Cocaine Abuse - 1

Phase 2
Completed
Conditions
Cocaine-Related Disorders
Registration Number
NCT00000324
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Brief Summary

The purpose of this study is to assess the efficacy of tryptophan vs. placebo, and voucher payments vs. a control condition, in the treatment of cocaine dependence.

Detailed Description

This clinical trial uses a 2 by 2 design to compare tryptophan to placebo, and voucher incentives vs. a control condition, in the outpatient treatment of cocaine dependence- using a relapse prevention model of treatment intervention.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Cocaine dependent
Exclusion Criteria
  • Physically dependent on drugs of abuse other than cocaine
  • Significant medical or psychiatric illness (besides substance abuse disorder)
  • Pregnant

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Side effects
Retention
Cocaine craving
Other drug use
Cocaine use
Psychosocial functioning
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Johns Hopkins University School of Medicine

🇺🇸

Baltimore, Maryland, United States

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