Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults

Completed

• Conditions: Development
• Interventions: Other: sweeteners

• Registration Number: NCT02646956
• Lead Sponsor: Monell Chemical Senses Center

Brief Summary

The goal of the study is to determine whether there are age-, diet- and genetically-related differences in the perception of sweeteners, both nutritive and non-nutritive.

Detailed Description

This is an observational 3-day study of children between the ages of 7 and 14 and their mothers. A variety of psychophysical methods determined liking for each of the sweeteners and saliva samples were obtained for genotyping of taste receptor genes. Anthropometric and dietary intake measures were also collected.

Study Timeline

• Study Start: 2014-05
• Primary Completion: 2015-09
• Study Completion: 2015-09
• Status Verified: 2015-12
• Study First Submitted: 2015-12-18
• Study First Submitted QC: 2016-01-04
• Last Update Submitted: 2016-01-04
• Study First Posted: 2016-01-06
• Last Update Posted: 2016-01-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 82

Inclusion Criteria

• Healthy

Exclusion Criteria

• Allergies and taking medication that affected taste

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Age Group-Children	sweeteners	Children between ages of 7 and 14
Age Group-Adults	sweeteners	Healthy adults who are the parent of the children

Primary Outcome Measures

Name	Time	Method
Liking for the taste of sweeteners measured via the 3-point facial hedonic scale.	Through study completion, an average of 6 months.
Liking for the taste of sweeteners measured via the Monell forced-choice, paired-comparison tracking procedure.	Through study completion, an average of 6 months.
Liking for the taste of sweeteners measured via the 5-point facial hedonic scale	Through study completion, an average of 6 months.

Secondary Outcome Measures

Name	Time	Method
BMI calculated from body weight and height measures	Through study completion, an average of 6 months	BMI will be calculated to examine associations between this measure and liking for sweeteners.
One day dietary intake collected via the Automated Self-Administered 24-hour dietary recall (ASA24).	Through study completion, an average of 6 months	Dietary recall will be completed to examine associations between added sugar intake and liking for sweeteners.
Genotyping of taste receptor genes via saliva donation	Through study completion, an average of 6 months	Genotyping will be completed to measure associations between individual taste receptor genotypes and liking of sweeteners.