Ultrastructure Analysis of Excised Internal Limiting Membrane in Eyes of Highly Myopia With Myopic Traction Maculopathy

Completed

• Conditions: Myopic Traction Maculopathy
• Interventions: Procedure: Vitrectomy with internal limiting membrane peeling

• Registration Number: NCT02528058
• Lead Sponsor: Kyorin University

Brief Summary

The excised ILM from 7 eyes of 7 patients with MTM including 7 eyes with macular retinoschisis and 4 eyes with foveal detachment but without any retinal break underwent vitrectomy with induction of posterior vitreous detachment and ILM peeling was examined to evaluate ultrastructure with electron microscopy.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06
• Primary Completion: 2014-07
• Study Completion: 2015-07
• Status Verified: 2015-08
• Study First Submitted: 2015-08-16
• Study First Submitted QC: 2015-08-17
• Last Update Submitted: 2015-08-17
• Study First Posted: 2015-08-19
• Last Update Posted: 2015-08-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 7

Inclusion Criteria

• The inclusion criteria were patients who underwent vitrectomy and internal limiting membrane peeling for myopic traction maculopathy and had a follow-up for more than 6 months.

Exclusion Criteria

• The patients with follow-up less than 6 months

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Myopic traction maculopathy	Vitrectomy with internal limiting membrane peeling	-

Primary Outcome Measures

Name	Time	Method
Visual acuity before and after surgery	6 months	Comparison in logarithm of Minimum Angle of Resolution (logMAR) vision

Secondary Outcome Measures

Name	Time	Method
Retinal reattachment	6 months	Resolution of macular retinoschisis and foveal detachment

Trial Locations

Locations (1)

Makoto Inoue; 🇯🇵 Mitaka, Tokyo, Japan