Chametherpay-induced nausea and vomitting treat with Fire Needle

Phase 1

Recruiting

• Conditions: Chametherpay-induced nausea and vomitting

• Registration Number: ITMCTR2100005252
• Lead Sponsor: The First Affiliated Hospital of Guangzhou University of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

?Patients with malignant tumor diagnosed by pathology or cytology, or imaging combined with specific tumor markers;
?Patients previously received or ongoing highly emetogenic chemotherapy combinations containing cisplatin or cyclophosphamide + anthracycline (AC regimen)and ect.;
?The antiemetic drugs used were 5HT3 receptor antagonist or NK1 receptor;
?Patients generally in good condition with the Karnofasky score greater than or equal to 60 and the estimated survival more than or equal to 5 months.
?Aged 18 to 75;
?Patients without severe cardiovascular, liver, kidney, bone marrow insufficiency and abnormal coagulation function;
?Patients who signed the informed consent and were willing to accept the treatment.

Exclusion Criteria

?Those who do not meet the above-mentioned inclusion criteria;
?Patients had been treated with acupuncture for other diseases during admission to pre-chemotherapy;
?Patients with nausea and vomiting due to brain metastases or limb metastases, or due to electrolyte disturbances and other systemic diseases such as severe diabetes;
?Patients with other severe infectious diseases, or with liver, kidney and cardiac insufficiency;
?Patients with mental retardation or a history of mental illness who are unable to conduct self-assessment;
?Patients who received radiotherapy during chemotherapy;
?Patients who cannot tolerate fire needles due to allergy, tension or other reasons.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MAT;No nausea rate;total control rate;Complete control rate;

Secondary Outcome Measures

Name	Time	Method
Simplified Nutritional Appetite Questionnaire;CTCAE V5.0;Hospital Anxiety and Depression Scale;