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Clinical Trials/NCT05600023
NCT05600023CompletedPhase 4

The Effectiveness of Single Antibiotic Paste Nitrofurantoin V/S Double Antibiotic Paste in Alleviation of Post-Operative Pain in Adult Patients Symptomatic Irreversible Pulpitis

Altamash Institute of Dental Medicine1 site in 1 country60 target enrollmentStarted: August 1, 2022Last updated:
Conditions
Interventions
Drugs

Trial Snapshot

Phase
Phase 4
Status
Completed
Enrollment
60
Locations
1
Primary Endpoint
To alleviate dental pain

Study Overview

Brief Summary

In our study, we used nitrofurantoin as a root canal medication in patients suffering from symptomatic irreversible pulpitis in alleviating pain compared with double antibiotic paste.

Detailed Description

This study aims to compare the efficacy in alleviating pain between intracanal medicaments Nitrofurantoin versus double antibiotic paste.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Single (Participant)

Eligibility Criteria

Ages
18 Years to 50 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • No medical history
  • no history of allergy to medications used in root canal treatment
  • patients suffering from Symptomatic Irreversible Pulpitis

Exclusion Criteria

  • Patients who were not suitable for conventional root canal treatment
  • multirooted teeth

Arms & Interventions

Nitrofurantoin

Experimental

Intervention: Nitrofurantoin (Drug)

Double antibiotic paste

Experimental

Intervention: Double Antibiotic (Drug)

Outcomes

Primary Outcomes

To alleviate dental pain

Time Frame: 12 hours upto 72 hours following placement of intracanal medicament

Dental pain will be measured by using Visual Analogue Scale(VAS) which is an 10-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Hira Abbasi

Principal Investigator

Altamash Institute of Dental Medicine

Study Sites (1)

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