The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste

Phase 4

Completed

• Conditions: Pain; Symptomatic Irreversible Pulpitis
• Interventions: Drug: Double Antibiotic; Drug: Nitrofurantoin

• Registration Number: NCT05600023
• Lead Sponsor: Altamash Institute of Dental Medicine

Brief Summary

In our study, we used nitrofurantoin as a root canal medication in patients suffering from symptomatic irreversible pulpitis in alleviating pain compared with double antibiotic paste.

Detailed Description

This study aims to compare the efficacy in alleviating pain between intracanal medicaments Nitrofurantoin versus double antibiotic paste.

Study Timeline

• Study Start: 2022-08-01
• Status Verified: 2022-10
• Primary Completion: 2022-10-24
• Study Completion: 2022-10-24
• Study First Submitted: 2022-10-25
• Study First Submitted QC: 2022-10-27
• Last Update Submitted: 2022-10-27
• Study First Posted: 2022-10-31
• Last Update Posted: 2022-10-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• No medical history
• no history of allergy to medications used in root canal treatment
• patients suffering from Symptomatic Irreversible Pulpitis

Exclusion Criteria

• Patients who were not suitable for conventional root canal treatment
• multirooted teeth

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Double antibiotic paste	Double Antibiotic	-
Nitrofurantoin	Nitrofurantoin	-

Primary Outcome Measures

Name	Time	Method
To alleviate dental pain	12 hours upto 72 hours following placement of intracanal medicament	Dental pain will be measured by using Visual Analogue Scale(VAS) which is an 10-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured

Trial Locations

Locations (1)

Hira Danish; 🇵🇰 Karachi, Sindh, Pakistan