RB-registry: a clinical registry for prospective data on retinoblastoma epidemiology and clinical course

Recruiting

• Conditions: C69.2; Retina

• Registration Number: DRKS00005423
• Lead Sponsor: niversitätsklinikum Essen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-12-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 550

Inclusion Criteria

•age at diagnosis younger than 18 years
•confirmed initial diagnosis of retinoblastoma
•new diagnosed constitutional pathogenic RB1 variant
•other pediatric eye tumor
•confirmed other malignancy in patients with constitutional RB1 variant
•no retinoblastoma-specific treatment prior to inclusion in RB-Registry
•written informed consent of the primary caregivers
•resident of Germany or Austria

Exclusion Criteria

Patients who do not fulfill the inclusion criteria

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
distribution of retinoblastoma international classification of retinoblastoma (ICRB) groups and international retinoblastoma staging system (IRSS) stages for patients diagnosed in Germany and Austria.

Secondary Outcome Measures

Name	Time	Method
Identification of variables influencing the course of disease in retinoblastoma patients,