Effects of Dairy- and Berry-based Snacks on Postprandial Glucose Metabolism in Older People

Not Applicable

Completed

• Conditions: Postprandial Hyperglycemia

• Registration Number: NCT04175353
• Lead Sponsor: University of Eastern Finland

Brief Summary

Malnutrition or its risk is common among older people. To maintain adequate nutrition, increased meal frequency is important. In addition to main meals, regular consumption of nutrient- and energy-dense snacks is recommended. The study examines the post-meal responses to dairy- and berry-based snacks tailored for older people. The plasma concentrations of glucose, insulin and free fatty acids are measured during three hours after snack consumption. In addition, subjective satiety responses and heart rate variability are recorded.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-02-01
• Primary Completion: 2016-06-02
• Study Completion: 2016-12-31
• Status Verified: 2019-11
• Study First Submitted: 2019-11-14
• Study First Submitted QC: 2019-11-22
• Last Update Submitted: 2019-11-22
• Study First Posted: 2019-11-25
• Last Update Posted: 2019-11-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• Home-dwelling

Exclusion Criteria

• Smoking
• Type 1 diabetes
• Type 2 diabetes treated with oral medications or insulin
• Cognitive impairment
• Antibiotic medication within the past 3 months
• Blood donation within the past month

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Change in postprandial glucose	3 hrs	Changes in plasma glucose concentration within 3 hrs after meal
Change in postprandial insulin	3 hrs	Changes in plasma insulin concentration within 3 hrs after meal

Secondary Outcome Measures

Name	Time	Method
Change in postprandial free fatty acids	3 hrs	Changes in plasma free fatty acid concentration within 3 hrs after meal
Change in postprandial satiety scores assessed by using visual analogy scales	3 hrs	Visual analogue scales (VAS) are used to assess satiety and other related subjective sensations (fullness, hunger, desire to eat, alertness) within 3 hrs after meal. Each VAS consists of a 100-mm horizontal line anchored with verbal descriptions at each end expressing the weakest (0 mm) or strongest (100 mm) statement of sensation. Results are scores between 0 and 100.
Heart rate variability	3 hrs	Electrocardiography monitoring for assessment of several variables of heart rate variability

Trial Locations

Locations (1)

University of Eastern Finland; 🇫🇮 Kuopio, Finland