Study of Light Treatment and Laser Treatment for Melasma

Not Applicable

Completed

• Conditions: Melasma
• Interventions: Procedure: Light Treatment; Procedure: Laser Treatment

• Registration Number: NCT00509977
• Lead Sponsor: Northwestern University

Brief Summary

The purpose of this study is to determine the efficacy of light treatment and laser treatment for melasma. These treatment options have not been thoroughly explored in the treatment of melasma. By studying the effect of different treatments, a better treatment plan may be developed for people with melasma.

Detailed Description

The objective of this study is to determine the efficacy of light treatment and laser treatment for melasma. These treatment options have not been thoroughly explored in the treatment of melasma. By studying the effect of different treatments, a better treatment plan may be developed for people with melasma.

Study Timeline

• Study Start: 2007-04
• Study First Submitted: 2007-07-31
• Study First Submitted QC: 2007-07-31
• Study First Posted: 2007-08-01
• Primary Completion: 2009-09
• Study Completion: 2009-09
• Status Verified: 2021-12
• Last Update Submitted: 2021-12-01
• Last Update Posted: 2021-12-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

• Diagnosis of melasma lesion measuring at least 4 square centimeters.
• Age 18-75 years.
• Good health.
• Willingness and ability to understand and provide informed consent for participation in the study.
• Ability to communicate with the investigator.
• Must be willing to forgo other treatment options for melasma during the course of the study.

Exclusion Criteria

• Inability to understand the protocol or to give informed consent.
• Mental illness.
• Under 18 years of age and over 75 years of age.
• Laser treatment in the last 6 months before enrollment.
• Isotretinoin within the past year.
• Lidocaine allergy.
• History of herpes simplex viral infection.
• Concurrent active disease to facial area (i.e acne).
• Bleeding disorder.
• History of abnormal wound healing.
• History of abnormal scarring.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
1	Light Treatment	Light therapy
2	Laser Treatment	Laser Treatment

Primary Outcome Measures

Name	Time	Method
Melasma Area and Severity Index	20 weeks

Secondary Outcome Measures

Name	Time	Method
Safety	20 weeks

Trial Locations

Locations (1)

Northwestern University Feinberg School of Medicine, Department of Dermatology; 🇺🇸 Chicago, Illinois, United States