AYURVEDIC MANAGEMENT OF GOUTY ARTHRITIS - A CLINICAL STUDY

Completed

• Conditions: Gout, unspecified. Ayurveda Condition: VATARAKTAM,

• Registration Number: CTRI/2021/04/032503
• Lead Sponsor: Dr SHILPA SHREE C

Brief Summary

THIS STUDY WAS PUT FORWARD TO EVALUATE THE EFFICACY OF VASADI KWATHA IN THE MANAGEMENT OF VATARAKTA WITH SPECIAL REFERENCE TO GOUTY ARTHRITIS IN COMPARISION WITH AMRITADI GUGGULU.

**HYPOTHESIS**:

1. **NULL HYPOTHESIS**

H0 :-THE EFFICACY OF VASADI KWATHA IS EQUIVALENT TO AMRITADI GUGGULU IN THE MANAGEMENT OF VATARAKTA WITH SPECIAL REFERENCE TO GOUTY ARTHRITIS.

2. **ALTERNATE HYPOTHESIS**

H1:-THE EFFICACY OF VASADI KWATHA IS GREATER THAN AMRITADI GUGGULU IN THE MANAGEMENT OF VATARAKTA WITH SPECIAL REFERENCE TO GOUTY ARTHRITIS.

H2:- THE EFFICACY OF VASADI KWATHA IS LESSER THAN AMRITADI GUGGULU IN THE MANAGEMENT OF VATARAKTA WITH SPECIAL REFERENCE TO GOUTY ARTHRITIS.



The study was completed with 30 subjects randomly allocated into 2 groups comprising15 subjects each. Subjects in Group A were treated with Vasadi Kwatha and Subjects in Group B were treated with Amritadi Guggulu for an intervention period of 30 days and follow up was for 15 days. Assessment was done on basis of both objective and subjective parameters on 0th day, 15th day, 30th day and 45th day.



On comparing the results between the groups, statistically non-significant results were obtained in all the parameters suggesting that, both Vasadi Kwatha and Amritadi Guggulu had equal effect in the management of Vatarakta. Thus,  Null hypothesis is accepted, i.e, The efficacy of Vasadi kwatha is equivalent to Amritadi Guggulu in the management of Vatarakta with special reference to Gouty Arthritis.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-09-04
• Study Completion: 2022-01-17
• Last Update Posted: 2022-08-04

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

SUBJECTS FULFILLING CRITERIAS OF AMERICAN COLLEGE OF RHEUMATOLOGY 1977 AND SUBJECTS WITH INCREASED LEVEL OF SERUM URIC ACID OF 7mg/dl to 10mg/dl IN MALE AND 6mg/dl to 10mg/dl IN FEMALE.

Exclusion Criteria

• SUBJECTS DIAGNOSED WITH OTHER INFLAMMATORY AND DEGENERATIVE JOINT DISEASE 2.
• SUBJECTS WITH HISTORY OF TRAUMA, FRACTURE JOINT, SURGICAL OR DIAGNOSTIC INTERVENTION WITH REFERENCE TO THE AFFECTED JOINT(S) IN PAST 1 YEAR.
• PREGNANT AND LACTATING WOMEN 4.
• SUBJECTS WITH ANY UNCONTROLLED SYSTEMIC ILLNESS INCLUDING DIABETES MELLITUS, HYPERTENSION.
• SUBJECTS WITH VATARAKTA WITH SPECIAL REFERENCE TO GOUTY ARTHRITIS PRESENTING WITH COMPLICATION INCLUDING JOINT DEFORMITIES.
• ANY OTHER CONDITION INTERFERING THE COURSE OF TREATMENT.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
REDUCTION IN THE LEVELS OF SERUM URIC ACID	30TH DAY, 45TH DAY

Secondary Outcome Measures

Name	Time	Method
REDUCTION IN THE CLASSICAL SIGNS AND SYMPTOMS OF VATARAKTA	REDUCTION IN THE SIGNS AND SYMPTOMS OF VATARAKTA ON 15th day, 30th DAY and 45th day

Trial Locations

Locations (1)

SRI SRI COLLEGE OF AYURVEDIC SCIENCE AND RESEARCH HOSPITAL; 🇮🇳 Bangalore, KARNATAKA, India

SRI SRI COLLEGE OF AYURVEDIC SCIENCE AND RESEARCH HOSPITAL

🇮🇳Bangalore, KARNATAKA, India

Dr SHILPA SHREE C

Principal investigator

9663684380

shilpa23197@gmail.com