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Clinical Trials/NCT06432842
NCT06432842
Recruiting
Not Applicable

Knee Osteoarthritis and Lazer Therapy

Karabuk University1 site in 1 country30 target enrollmentJuly 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Knee Osteoarthritis
Sponsor
Karabuk University
Enrollment
30
Locations
1
Primary Endpoint
Pain severity
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

Osteoarthritis (OA) is a chronic degenerative disease of articular cartilage that causes hypertrophic changes in bone. OA is a non-inflammatory progressive musculoskeletal disease and is one of the most common degenerative diseases in the general population. OA is characterized by progressive cartilage destruction in load-bearing joints, subchondral sclerosis, osteophyte formation, and some biochemical and morphological changes in the synovial membrane and joint capsule. Common symptoms of knee osteoarthritis are; Knee pain that increases with activity, limitation of normal joint movement of the knee, edema, and knee pain that begins with prolonged sitting.

The aim of this study is to evaluate the effects of laser treatment applied in addition to conventional physiotherapy on pain, function, muscle strength and balance in patients with knee osteoarthritis who received PRP.

Detailed Description

OA is a non-inflammatory progressive musculoskeletal disease; damage begins in the cartilage and causes changes in the joint structure over time. Although intra-articular injection approaches have been frequently used in the treatment of OA recently, intra-articular injections known as Platelet Rich Plasma (PRP) have also started to be used frequently. Today, the areas of use of laser therapy have increased. When the laser beam is applied, it is absorbed by the tissue or scattered back. Laser has photochemical, thermal and ionizing effects on tissues. Laser has an analgesic effect by increasing endorphin synthesis and reducing C nerve fiber activation. Laser indirectly increases microcirculation by increasing temperature in the tissue. Although there are various studies on treatment options for OA in the literature, no studies have been found to investigate the effectiveness of laser treatment applied in addition to conventional treatment after PRP. In our study, we aimed to evaluate the effects of laser treatment applied in addition to conventional physiotherapy on pain, function, muscle strength and balance in patients with knee osteoarthritis who received PRP.

Registry
clinicaltrials.gov
Start Date
July 1, 2023
End Date
June 30, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Karabuk University
Responsible Party
Principal Investigator
Principal Investigator

METEHAN YANA

Director

Karabuk University

Eligibility Criteria

Inclusion Criteria

  • Volunteering to participate in the study
  • Being diagnosed with knee OA by a specialist physician
  • Having had PRP injection applied by a specialist physician
  • Having unilateral knee OA
  • Being stage I-stage III in the Kellgren-Lawrence OA classification
  • Being between the ages of 18-65

Exclusion Criteria

  • Being stage IV in the Kellgren-Lawrence OA classification
  • BMI being more than 40 kg/m2
  • Patients who do not cooperate well
  • Patients with neurological or neuromuscular disease

Outcomes

Primary Outcomes

Pain severity

Time Frame: Baseline and 2 weeks post-intervention

Knee pain severity will measured using the Visual Analog Scale. Scale (VAS). The VAS is a 10 cm scale, where 0 represented no pain and 10 represented unbearable pain. Pain intensity was recorded by measuring the point marked between 0- 10.

Function

Time Frame: 2 weeks post-intervention

WOMAC will be used to evaluate the degree of physical function. This scale has a total of 24 questions and 5 answers between 0-4 for each question. A high score indicates that the symptoms are severe.

MUSCLE STRENGTH

Time Frame: Baseline and 2 weeks post-intervention

Hip, knee flexor and extensor muscle strengths will be measured using a manual dynamometer.

BALANCE

Time Frame: Baseline and 2 weeks post-intervention

Dynamic balance of individuals through the Modified Star Balance Test will be evaluated.

Study Sites (1)

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