NL-OMON56803
尚未招募
不适用
Acute effects of ketone monoester supplementation on brain function in older men with overweight - Ketone monoesters and brain function
概览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 36
概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 65 至 99（—）
入选标准
- •\- Men, aged between 60\-75 years
- •\- BMI between 25\-30 kg/m2
- •\- Fasting plasma glucose \< 7\.0 mmol/L
- •\- Fasting serum total cholesterol \< 8\.0 mmol/L
- •\- Fasting serum triacylglycerol \< 4\.5 mmol/L
- •\- Systolic blood pressure \< 160 mmHg and diastolic blood pressure \< 100 mmHg
- •\- Stable body weight (weight gain or loss \< 3 kg in the past three months)
- •\- Willingness to give up being a blood donor from 8 weeks before the start of
- •the study, during the study and for 4 weeks after completion of the study
- •\- No difficult venipuncture as evidenced during the screening visit
排除标准
- •\- Left\-handedness
- •\- Following a low\-carbohydrate diet or consuming nutritional ketone supplements
- •\- Current smoker, or smoking cessation \< 12 months
- •\- Diabetic patients
- •\- Familial hypercholesterolemia
- •\- Abuse of drugs
- •\- More than 3 alcoholic consumptions per day
- •\- Use of products or dietary supplements known to interfere with the main
- •outcomes as judged by the principal investigators
- •\- Use medication to treat blood pressure, lipid or glucose metabolism, or
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