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Clinical validation of the dried blood spot analysis for antituberculosis drugs

Completed
Conditions
Blood concentration of anti TB drugs
10028440
Registration Number
NL-OMON34891
Lead Sponsor
niversitair Medisch Centrum Groningen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
33
Inclusion Criteria

- Adult (>18 years old)
- TB-patient who using at least one of the following drugs: Isoniazid, Pyrazinamide, Rifampicin, Ethambutol, clarithromycin, Amikacin, Kanamycin, Moxifloxacin, Linezolid
- TB-patient who is scheduled for routine TDM by the doctor.
- written informed consent

Exclusion Criteria

Patients with serious bleeding disorder

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The correlation of laboratory analysis results from DBS method to conventional<br /><br>method</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>The influence of origin of the bloodsample (finger prick or venous blood) on<br /><br>the concentration of the drug and its effect on DBS results </p><br>
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