Genital and subjective sexual response in women after close rectal restorative proctocolectomy with ileal pouch anal anastomosis: a comparative clinical study
- Conditions
- imflammatory disease of the large intestineulcerative colitis100179691001335610017998
- Registration Number
- NL-OMON34030
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 18
Inclusion Criteria
Female patients
>17 years and pre menopausal
Ulcerative colitis
Scheduled for elective restorative procotocolectomy with IPAA; or
Scheduled for completion proctectomy with IPAA
Exclusion Criteria
*Previous bowel resections other than emergency colectomy
Previous surgery on genitalia
Non elective surgery
Severe postoperative complications (e.g. anastomotic leakage, abscess, peritonitis)
Use of medication that might influence the sexual response (psychopharmaca, antihypertensives)
Diabetes Mellitus
Depression (measured by Beck Depression Inventory (BDI)- Scale)
History of sexual abuse
Pre-existence of sexual dysfunction
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Primary endpoint is the difference in VPA pre- and postoperatively. The results<br /><br>are compared to those of the Plexlab study.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary endpoints are differences in feelings of sexual arousal and estimated<br /><br>lubrications pre- and postoperatively and difference in psychological- and<br /><br>sexual functioning pre- en postoperatively. The results are compared to those<br /><br>of the Plexlab study.</p><br>