NL-OMON41127已完成不适用
A randomized, cross-over, dose-response trial of tyrosine and its effect on working memory in healthy elderly and young people - FOCOM DoReTy study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Aged 18-35 years or aged 60-75 years
- •Normal and stable weight (BMI 18.5-25 kg/m2 and weight 50-95 kg)
- •Willing to abstain from blood donation during the study
- •Dutch-speaking
- •Non-smoking
- •Normal or corrected-to-normal vision
排除标准
- •Thyroid problems, such as hyperthyroidism, hypothyroidism, thyroid cancer
- •Using medication that can interfere with tyrosine*s action; monoamine oxidase inhibitors and other antidepressants, sympathomimetic amines, and opioids
- •Following a low-protein diet as prescribed by a dietician or physician
- •Parkinson*s Disease
- •Depression
- •Use of tyrosine supplements
- •Being allergic or having a dislike to the product carrier (banana-flavored yoghurt)
- •Bad venous access, as judged by the research nurse
- •Mini Mental State Examination (MMSE) score < 24 (to exclude cognitive impaired participants, only for elderly participants)
- •Estimated IQ < 85 (based on Nederlandse Leestest voor Volwassenen (NLV) -score)
- •(History of) clinically significant psychiatric disorder
- •(History of) clinically significant neurological disorder, such as brain infarct, chronic migraine, major depression
- •Under treatment for cardiac or vascular diseases and use of medication for these conditions
- •General medical conditions, such as repetitive strain injury (RSI) or sensori-motor handicaps, as judged by the investigator
- •Alcohol consumption of more than 14 (women) or 21 (men) units per week
研究者
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