Discussion on the prevention of recurrence and inflammatory gland transformation after surgery for colorectal adenomas with modified Shenling Baizhu powder based on the theory of spleen deficiency dampness and blood stasis, and the influence on the biological characteristics of intestinal flora.
- Conditions
- Colorectal adenoma
- Registration Number
- ITMCTR2024000039
- Lead Sponsor
- The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) Colorectal polyps found by colonoscopy and endoscopic polypectomy were performed, which met the diagnostic criteria for colorectal adenoma after surgery;
(2) Meet the diagnostic criteria for spleen deficiency and dampness stasis syndrome in traditional Chinese medicine;
(3) Age between 18-70 years old, gender is not limited;
(4) Not taking relevant drugs that may prevent the effects of drugs, such as aspirin, celecoxib, folic acid tablets, berberine, etc.;
(5) Patient informed consent and signed consent form;
(1) There are serious complications, such as intestinal root obstruction, gastrointestinal bleeding, etc.;
(2) Those who have been pathologically confirmed to have cancer
(3) Combined with other such as serrated polyps, juvenile polyposis syndrome, familial adenomatous polyposis, etc.;
(4) Those who suffer from mental disorders and are unable to cooperate with clinical diagnosis and treatment;
(5) Pregnant women or lactating women;
(6) Patients with other serious primary diseases, such as liver, kidney, cardiopulmonary organ damage;
(7) Those with allergies or a history of allergies to multiple drugs
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method TCM symptom score evaluation;Biological characteristics of the gut microbiota;Pathological examination;Tumor Necrosis Factor alpha (TNF-a);Colonoscopy;Interleukin-8(IL-8);Interleukin-6 (IL-6);
- Secondary Outcome Measures
Name Time Method Evaluation of recurrence;