EFFECT OF KUSHMANDA GRANULES IN THE MANAGEMENT OF GARBHODAKA KSHAYA W.S.R TO OLIGOHYDRAMNIOS- A RANDOMIZED OPEN LABELLED STANDARD CONTROLLED CLINICAL TRIAL

Information on the Trial procedure and Drug: Here in Group A- Kushmanda Granules 5 gm orally twice a day with milk for 15 days*.* In Group B- L- arginine sachet 10gm in divided doses orally with water. We assure that we will prepare formulations as per S.O.P in the pharmacy of I.T.R.A.

**Description of the Process:**In present study, participants who will be clinically diagnosed and confirmed cases of Garbhodaka Kshaya (Oligohydramnios) enlisted in inclusion criteria will be enrolled. All patients will be divided into two groups by computer generated randomisation technique, having minimum of 10 patients in one group. Group A will be given with Kushmanda Granules 5 gm orally twice a day with milk for 15 days. And Group B will be given with L- arginine sachet 10gm in divided doses orally with water

Follow-up: Patients will be advised to visit the hospital every 5th day during the treatment for

15 days and then after7 days after treatment as a follow up.

Side Effects: We will follow closely and keep track of any unwanted effects. We may use some other medicines or stop the usage of drug to decrease the symptoms of the side effects.

Results: The efficacy of the therapy will be assessed on the basis of subjective and objective criteria.

Benefits: Project will help us to resolve the research question. There may not be any benefit for the society at this stage of the research, but future generations are likely to be benefited as to find out proper treatment protocol for the management of Garbhodaka Kshaya (Oligohydramnios). Collected information from this research project will be kept confidential, all outcomes will be noted in tabular form and appropriate statistical tests will be applied to compare the effect