The Change of Plasma Fibrinogen Level Following Laparoscopic Bariatric Surgery: A Prospective Study in Morbidly Obese Malaysian.

Completed

• Conditions: Morbid ObesityDeep vein thrombosis Pulmonary embolism; Fibrinogen,; weight loss,; morbid obesity; bariatric surgery; Deep vein thrombosis

• Registration Number: TCTR20220719007
• Lead Sponsor: /A

Brief Summary

Metabolic surgery results in a drop in plasma fibrinogen levels as early as three months postoperatively in the Malaysian obese population. There is a significant correlation between the levels of plasma fibrinogen and excess BMI loss, regardless of whether sleeve gastrectomy or Roux-en-Y gastric bypass surgery is performed. This may suggest that weight reduction after metabolic surgery may result in a lower risk of thrombosis.

Detailed Description

Not available

Study Timeline

• Study Completion: 2016-03-01
• Study Start: 2022-07-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 51

Inclusion Criteria

morbidly obese patient with BMI > 32.5 kg/m2 or indicated for bariatric surgery, aged 18 to 65 years old and Malaysian nationality.

Exclusion Criteria

Pre-existing thromboembolic disease (DVT or PE), underlying clotting disorders or deranged liver enzymes, on anticoagulant or antiplatelet therapy and pregnant patients were excluded.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma fibrinogen 3months g/

Secondary Outcome Measures

Name	Time	Method
Change in body mass index 3months kg/m2