ong-term Effect of Tolvaptan Administration for Outcome and Neurohormonal Factors in Patients with Heart Failure
Not Applicable
- Conditions
- heart failure
- Registration Number
- JPRN-UMIN000013807
- Lead Sponsor
- ihon University Surugadai Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with a history of hypersensitivity for tolvaptan or an analogue. Anuresis or hypernatremia. Patients who have difficulty with fluid intake or can not feel dipsesis. Pregnant woman or possibility of the pregnancy. Patients whom tolvaptan is already given at registration. Patients whom study responsibility physician judged inappropriate.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The changes in neurohormonal factors (catecholamine, renin activity, aldosterone, copeptin)
- Secondary Outcome Measures
Name Time Method The finding of fluid retention, the changes in serum sodium, BUN, Cr, urinary L-FABP, dosage of diuretics, blood pressure, heart rate and 6-month prognosis (readmission and death)