Role of local application of insulin on diabetic wound healing
- Conditions
- Health Condition 1: E108- Type 1 diabetes mellitus with unspecified complications
- Registration Number
- CTRI/2021/05/033671
- Lead Sponsor
- Kasturba Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 54
•Patients with diabetic ulcers (both type 1 & type 2) in lower limbs.
•Patients who are above 18 years of age
•Patients with ulcer area of <= 30cm2.
•Patients with Grade 0, 1 and Stage A, C according to University of Texas Diabetic Wound classification.
•Patients who are willing to participate in study voluntarily.
• Patients with Grade 2, 3 and Stage B, D according to University of Texas Diabetic wound classification.
• Patients with peripheral vascular disease as in those who have monophasic flow in ultrasound
doppler.
• Burns wounds and Pressure sores
• Patients with venous ulcers.
• Patients more than 70 years old.
• Patients on systemic steroid therapy or immune-compromised patients.
• Non compliant patients.
• Patients with GRBS <100 mg/dl before the dressing.( Safety check)
• Pregnant female patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the effect of Topical insulin dressings over the routine saline dressings by comparing percentage reduction in the surface area of the ulcer.Timepoint: 15 days
- Secondary Outcome Measures
Name Time Method To evaluate the efficacy of Topical insulin application on reducing the wound healing time by comparing the time taken for the ulcer to decrease in size.Timepoint: 15 days