Effect of oxycodone on immune function and inflammatory factors after laparoscopic colorectal tumor resection
- Conditions
- colorectal neoplasia
- Registration Number
- ChiCTR2400089072
- Lead Sponsor
- Huazhong University of Science and Technology Union Shenzhen Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
18 years = age =60 years; Not limited to men and women, nationality; General anesthesia surgery, the expected operation time is more than 2 hours, and the operation end time is before 12:00pm; Solicit comments from patients or their families and agree to participate in this trial.
He was admitted to ICU directly after surgery. Pregnancy or lactation; Had a solid organ or bone marrow transplant; Diseases that may affect immune-related indicators, such as autoimmune diseases such as rheumatoid arthritis and SLE or malignant hematological tumors (leukemias and lymphomas, etc.); Acute brain injury (traumatic brain injury, subarachnoid hemorrhage, acute ischemic stroke, acute intracranial hemorrhage, acute intracranial infection); Chronic kidney disease; Acute myocardial infarction or severe heart failure (NYHA: Level 4); Severe chronic liver disease (Child-Pugh: Grade C); Deafness, aphasia, mental illness or severe cognitive impairment; Tracheal catheter was removed within 24 hours after operation. Unwillingness or unwillingness to provide informed consent or poor compliance.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cytokines and lymphocyte subsets;
- Secondary Outcome Measures
Name Time Method VAS scores;Subjective sleep rating;