Effect if Simvastatin (Drug) in Liver Cirrhosis
Not Applicable
- Conditions
- Health Condition 1: K746- Other and unspecified cirrhosis ofliver
- Registration Number
- CTRI/2021/12/038917
- Lead Sponsor
- Institute of Liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Diagnosed case of Hepato-pulmonary syndrome AaPO2 > 15 mm Hg on standing room air arterial blood gas (ABG). PaO2 <80 mmHg for clinical HPS between 18-70 years of years
2) Child A/B cirrhosis, Child C with CTP score of
more than equals to 10
3) Patient with no liver transplant option
Exclusion Criteria
1) Child-C cirrhosis CTP >10
2) Very Severe HPS
3) Acute-on-chronic liver failure
4) Thrombosis of splenoportal axis
5) Hepatocellular carcinoma
6) Renal dysfunction
7) Patients intolerant to beta blockers (history of hypotension or bradycardia)
8) Contraindication for beta-blockers (history of chronic obstructive pulmonary disease, atrioventricular block)
9) Pregnant females
10) Refusal to participate in the study
11) Hepatic Hydrothorax
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method