Pronostic Impact of Flow Fraction Reserve on Intermediate Stenoses

Completed

• Conditions: Coronary Stenosis

• Registration Number: NCT03588455
• Lead Sponsor: Fondation Hôpital Saint-Joseph

Brief Summary

The intermediate coronary stenoses defined by a degree of stenosis from 40 to 70 % are frequent. The Flow Fraction Reserve (FFR), realized during coronarography, is an hemodynamic evaluation by the functional impact measuring the loss of load in upstream / approval of the stenosis inthe basal state and in situation of hyperemia led by adenosine. Further to the study FAME, the threshold of definition of the significant character of one Stenosis was fixed for a value of FFR = 0,80. However, the impact forecasts intermediate values badly known rest.

We hypothetized that coronary stenosis associated with borderline values of FFR 0.81-0.85 were associated with a higher rate of clinical events than those with a FFR \>0.85

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-01
• Primary Completion: 2018-04-30
• Study Completion: 2018-06-30
• Study First Submitted: 2018-07-04
• Study First Submitted QC: 2018-07-04
• Study First Posted: 2018-07-17
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-07
• Last Update Posted: 2018-08-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 91

Inclusion Criteria

• patient with FFR> 0,80 between september 2012 till december 2016

Exclusion Criteria

• refusal of participation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Composite outcome	3 years	cardiovascular mortality or acute coronary syndrom or revascularization or cardiovascular rehospitalisation

Trial Locations

Locations (1)

Groupe Hospitalier Paris Saint Joseph; 🇫🇷 Paris, Ile-de-France, France