The Effectiveness of Sublingual or Oral Administration Misoprostol for Cervical Ripening before Manual Vacuum Aspiration in First Trimester Termination of Pregnancy: Randomized Controlled Trial
Phase 3
Completed
- Conditions
- First trimester termination of pregnancyThe effectiveness of Misoprostol for cervical preparation before manual vacuum aspirationfirst trimester abortionmisoprostolcervical dilatationmanual vacuum aspiration
- Registration Number
- TCTR20140427001
- Lead Sponsor
- Faculty of medicine, Thammasat University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
A singleton intrauterine pregnancy equal or less than 12 weeks gestational age with a diagnosis of early pregnancy failure blighted ovum anembryonic gestation and embryonic death no cardiac activity visible on TVS when the embryo measures 5 mm or more in length The gestational age was verified by a reliable menstrual history and confirmed by physical or ultrasound examination
Exclusion Criteria
A history of misoprostol allergy
anticoagulant usage
clinical coagulopathy
bleeding disorder
hypertension
chronic illness
active pelvic inflammatory disease
inevitable and incomplete abortion
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method cervical dilatation was measured prior to Manual Vacuum Aspiration The cervical width was measured prior to Manual Vacuum Aspiration cervical width was measured by largest Hegar’s dilators that pass through cervix without resistance
- Secondary Outcome Measures
Name Time Method pain scores and patient satisfactions after finished manual vacuum aspiration visual analogue 10cm-scale with zero to 10