Effect of short term versus extended period early intensive conventional insulin therapy on beta cell function, insulin resistance, glycemic control and long term remission rate in newly diagnosed type 2 diabetes: a randomized parallel group trial

CSIR NewDelhi0 个研究点目标入组 220 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1.Newly diagnosed T2DM patients (treatment naÃ¯ve, less than six months since diagnosis) of both sexes aged 25-65 years who have failed to diet and exercise therapy alone (diagnosis would be based on American Diabetes Association recommendations)
•2.Willing to give informed consent after explaining the purpose, nature and potential risks of the study

•1.Acute or severe chronic diabetic complications
•2.Severe intercurrent illness(the condition or the treatment there of is likely to affect the study outcomes)
•3.Impaired renal functions (S. Creatinine 1.5 mg% in males and 1.4 mg% in females)
•4.Impaired hepatic functions (Serum bilirubin, SGOT, SGPT, and Alkaline phosphatase 1.5 times the upper limit of normal)
•5.Tested positive for glutamic acid decarboxylase antibody
•6.Maturity onset diabetes in youth (exclusion by history)
•7.Patients requiring 1.3U/kg body weight of insulin at the end of titration phase.
•8.Pregnancy / lactation
•9.Malignancy (previously documented)
•10.Ischemic heart disease (previously documented)

发起方

CSIR NewDelhi