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A cohort study of anticholinergic drugs in South Asian women with detrusor overactivity

Phase 1
Conditions
The medical condidtion is overactive bladder .A wide range of different anticholinergic agents is available to treat overactive bladder (OAB) symptoms.Within the last 15 years, ethno-pharmacologic research has uncovered significant differences in how people in diverse ethnic groups metabolize certain drugs.
Registration Number
EUCTR2006-001210-33-GB
Lead Sponsor
niversity Hospitals of Leicester NHS Trust
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Female
Target Recruitment
50
Inclusion Criteria

Inclusion criteria
•Eligible patients will be from South Asian women or Caucasian women aged 18 or over with urodynamically proven detrusor overactivity (DOA).
•No anticholinergic medication over the previous two months
•No contraindications to the use of anticholinergic agents.
•Ability to provide fully informed consent.

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Women who have a contraindication to the use of anticholinergic drugs.
Women with coexisting bladder neck weakness (stress incontinence).
Women who have been treated with anticholinergic medication in the previous three months.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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