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Clinical Trials/ACTRN12614000766617
ACTRN12614000766617
Terminated
Phase 3

The effect of combining manual therapy with exercise for stable mild chronic obstructive pulmonary disease: arandomised controlled trial

Macquarie University0 sites81 target enrollmentJuly 18, 2014

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Chronic obstructive pulmonary disease
Sponsor
Macquarie University
Enrollment
81
Status
Terminated
Last Updated
6 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
July 18, 2014
End Date
TBD
Last Updated
6 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • 1\. Existing diagnosis of mild COPD (60% \< FEV1 \< 80%)
  • 2\. Stable COPD (no exacerbations for preceding 6 months)
  • 3\. Current non\-smoker (non\-smoking for \> 6 months)

Exclusion Criteria

  • 1\. Inability to complete 6 minute walking test unassisted
  • 2\. History of auto\-immune disease that may have permanently altered systemic inflammatory biomarkers
  • 3\. Contra\-indication for thoracic spinal manipulation (Bone density T score \< \-2\.5 and/or Z score \< \-1\)
  • 4\. Thoracic joint instability
  • 5\. Acute pain on thoracic joint range of motion testing
  • 6\. Below normal chest wall musculature for age and gender
  • 7\. High level of anxiety related to receiving thoracic spinal manipulation
  • 8\. Completed a pulmonary rehabilitation program within the previous 12 months

Outcomes

Primary Outcomes

Not specified

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