The effect of combining manual therapy with exercise for stable mild chronic obstructive pulmonary disease: arandomised controlled trial

Phase 3

• Conditions: Chronic obstructive pulmonary disease; Respiratory - Chronic obstructive pulmonary disease

• Registration Number: ACTRN12614000766617
• Lead Sponsor: Macquarie University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-07-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 81

Inclusion Criteria

1. Existing diagnosis of mild COPD (60% < FEV1 < 80%)
2. Stable COPD (no exacerbations for preceding 6 months)
3. Current non-smoker (non-smoking for > 6 months)

Exclusion Criteria

1. Inability to complete 6 minute walking test unassisted
2. History of auto-immune disease that may have permanently altered systemic inflammatory biomarkers
3. Contra-indication for thoracic spinal manipulation (Bone density T score < -2.5 and/or Z score < -1)
4. Thoracic joint instability
5. Acute pain on thoracic joint range of motion testing
6. Below normal chest wall musculature for age and gender
7. High level of anxiety related to receiving thoracic spinal manipulation
8. Completed a pulmonary rehabilitation program within the previous 12 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified