NCT00457587进行中（未招募）不适用
Präklinische Studie Zur Etablierung Einer Immuntherapie für Das Nebennierenrindenkarzinom - Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma
University of Wuerzburg2 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2005年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- To find reasonable antigens for a vaccination therapy in ACC
研究概览
简要总结
Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. Surgical resection of the tumor is the treatment of choice. However, even after complete resection more than 80 % of patients will experience recurrence of disease. Therefore, new treatment options are urgently needed. This pre-clinical study try to lay the foundations for a successful immunotherapy in patients with ACC.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients with histological proven adrenocortical carcinoma
- •healthy persons as control group
- •Life expectancy > 6 months
排除标准
- •autoimmune diseases
- •severe clinical condition
结局指标
主要结局
To find reasonable antigens for a vaccination therapy in ACC
时间窗: day of blood sampling
To investigate the role of tumor-induced suppression in ACC
时间窗: NA, in vitro study
次要结局
未报告次要终点
研究者
Martin Fassnacht
Professor for Internal Medicine and Endocrinology
University of Wuerzburg
研究点 (2)
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