Prediction of Chronic Postsurgical Pain in Adults

Completed

• Conditions: Acute Post Operative Pain; Chronic Postsurgical Pain
• Interventions: Procedure: Cardiothoracic surgery; Procedure: Breast surgery; Procedure: Gastrointestinal surgery; Procedure: Genitourinary surgery; Procedure: Orthopaedic surgery

• Registration Number: NCT04866147
• Lead Sponsor: University of Aarhus

Brief Summary

This research will be a prospective single-centre observational cohort study in Denmark spanning approximately one year. The objective of this study is to develop a clinically applicable and generalizable prediction model for postsurgical pain in adults.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-04-26
• Study First Submitted QC: 2021-04-26
• Study First Posted: 2021-04-29
• Study Start: 2021-05-25
• Primary Completion: 2023-05-15
• Study Completion: 2023-08-15
• Status Verified: 2023-10
• Last Update Submitted: 2023-10-10
• Last Update Posted: 2023-10-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1522

Inclusion Criteria

• Consenting Danish-speaking adults aged 18 years and older
• Patients who undergo common inpatient or outpatient surgical procedures

Exclusion Criteria

• Patients with cognitive impairment
• Patients who refuse or unable to provide informed consent
• Patients who undergo re-operation within 3 months of their initial surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Surgery patients	Cardiothoracic surgery	Patients who undergo various common surgical procedures
Surgery patients	Gastrointestinal surgery	Patients who undergo various common surgical procedures
Surgery patients	Breast surgery	Patients who undergo various common surgical procedures
Surgery patients	Genitourinary surgery	Patients who undergo various common surgical procedures
Surgery patients	Orthopaedic surgery	Patients who undergo various common surgical procedures

Primary Outcome Measures

Name	Time	Method
Chronic post surgical pain	3 months post surgery	Pain related to the surgical procedure measured as average pain intensity on rest or movement using 11-point numeric rating scale (NRS; 0-10) where 0=no pain and 10=worst pain imaginable and/or average pain interference using 11-point NRS among any one of seven short-form Brief Pain Inventory items (general activity, mood, walking ability, normal work (including housework), relations with other people, sleep, enjoyment of life) in the past one week, where 0=pain does not interfere and 10=pain completely interferes.

Secondary Outcome Measures

Name	Time	Method
Acute post surgical pain	First 3 hours after surgery	Acute post surgical pain intensity in the first 3 hours after surgery measured as pain at rest using 11-point numeric rating scale (NRS; 0-10) where 0=no pain and 10=worst pain imaginable.

Trial Locations

Locations (2)

Aarhus University Hospital; 🇩🇰 Aarhus N, Denmark

Silkeborg Regional Hospital; 🇩🇰 Silkeborg, Denmark