A Community Trial to Determine Whether 'Safe Storage' Reduces Pesticide Self-poisoning in Rural Asia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 223,861
- 试验地点
- 1
- 主要终点
- Incidence of Pesticide Self-poisoning
研究概览
简要总结
A major global public health priority is to identify effective methods for preventing deaths from pesticide self-poisoning. The aim of this work is to determine whether the provision of lockable storage containers to poor households in rural Asia can reduce the incidence of intentional pesticide self-poisoning. Secondary questions include the effect of these containers on unintentional pesticide poisoning in children and overall self-harm.
详细描述
We will set up a large community-based, cluster randomised controlled trial of 162 villages (mean adult population 900) in rural Sri Lanka to determine the effectiveness and cost of the provision of safe storage containers to prevent pesticide poisoning.
The study will be based in Anuradhapura District where we have carried out public health studies of pesticide poisoning since 2002. 81 intervention and 81 control villages will be recruited. Randomisation will be clustered, with villages rather than households randomised. A census will be performed at baseline and after 3 years to establish the population demographics and number of person-years exposed.
The primary outcome will be the incidence of pesticide self-poisoning; secondary outcomes will be the incidence of all self-poisoning, all self-harm, fatal self-harm, pesticide poisoning and unintentional paediatric pesticide poisoning. We will use Poisson regression models, taking account of clustering and stratification, for the analysis.
The study will provide definitive evidence concerning the cost-effectiveness of this approach that will determine whether it should be promoted across Asia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Any village in the study area that gives consent to the study
排除标准
- 未提供
研究组 & 干预措施
Storage container
Ultraviolet light resistant plastic in-ground pesticide storage container
干预措施: Ultraviolet light-resistant plastic in-ground pesticide storage container (Device)
Control
结局指标
主要结局
Incidence of Pesticide Self-poisoning
时间窗: For three years after intervention
Cases identified by survey of local and referral hospitals and by regular interview of primary informants in each village
次要结局
- Incidence of All Self-poisoning(For three years post-intervention)
- Incidence of All Self-harm(For three years after intervention)
- Incidence of Fatal Self-harm(For three years post intervention)
- Incidence of Pesticide Poisoning(For three years post intervention)
- Incidence of Unintentional Paediatric Pesticide Poisoning(For three years post intervention)