To analyse if T.Metformin along with lifestyle modification is better than only lifestyle modification is treatment of adolescent PCOS.
Phase 2
- Conditions
- Health Condition 1: N915- Oligomenorrhea, unspecified
- Registration Number
- CTRI/2023/10/058811
- Lead Sponsor
- Sri Manakula vinayagar medical college and hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Irregular cycle, clinical hyperandrogenism, biochemical hyperandrogenism
Exclusion Criteria
Primary amenorrhea due to structural deformities, regular cycle, gastritis, gastric ulcer, liver disease, depression or bipolar disorder, contraindication to exercise.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the effect of tablet metformin on biochemical parameters like lutenizing hormone, toral testosterone, lipid profile, HbA1C in adolescent PCOS.Timepoint: 3months
- Secondary Outcome Measures
Name Time Method To compare the effect of tablet metformin and lifestyle modification versus placebo and lifestyle modification for 3months in regularising the menstural cycles, reducing hirsutism, acne and obesity in adolescent PCOSTimepoint: 3months