The effect of bupropion on impotence in female MS patients

Phase 2

Recruiting

• Conditions: Condition 1: Multiple Sclerosis. Condition 2: Sexual dysfunction.; Multiple sclerosis; Sexual dysfunction not due to a substance or known physiological condition

• Registration Number: IRCT20140105016087N2
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 May 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

Adult women over 18 years
The duration of MS is more than six months
Having sexual activity in the last six months
Not known to have an acute mental disorder
Husband monogamy

Exclusion Criteria

Moderate to severe depression with HADS questionnaire (score 11 and above)
Consumption of silicotropic drugs and benzodiazepines and SSRIs during the study
Known for acute mental disorder
Pregnancy or breastfeeding
Peripheral problems of the genitourinary system lead to sexual dysfunction
Facing severe crises such as the death of loved ones during the last six months
Withdrawal from study and incomplete answers to the questionnaires so that more than 20% of the questions in each questionnaire are unanswered.
History of seizures
History of bulimia and anorexia

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intimacy and sexual activity in MSISQ 19 questionnaire. Timepoint: The beginning of the study, the sixth week and the twelfth week. Method of measurement: MSISQ 19 questionnaire.;Percentage of people with a depression score of less than 11 on the HADS questionnaire. Timepoint: The beginning of the study. Method of measurement: HADS questionnaire.

Secondary Outcome Measures

Name	Time	Method
Multiple Sclerosis Quality Of Life. Timepoint: The beginning of the study-End of study. Method of measurement: (MSQOL-54).;Fatigue. Timepoint: The beginning of the study. Method of measurement: The Multidimensional Fatigue Inventory.;Sphincter disorders. Timepoint: The beginning of the study. Method of measurement: Sphincter Disorder Questionnaire.