Clinical efficacy of endodontic protocols on reduction of cultivable bacteria and endotoxin in infected root canal in patients who have undergone radiation therapy to the head and neck
- Conditions
- Periapical periodontits. Cancer.
- Registration Number
- RBR-2t6zbhf
- Lead Sponsor
- universidade estadual paulista
- Brief Summary
This clinical study demonstrated that endodontic treatment in irradiated patients may be efficacious.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Terminated
- Sex
- Not specified
- Target Recruitment
- Not specified
Patients who have undergone radiation therapy of at least 50 Gy for malign tumor in the head and neck needing primary endodontic treatment were included in this clinical research. Only single-rooted teeth with diagnostic of primary endodontic infection that was confirmed by a negative response to cold thermal testing with difluorodichloromethane at -50°C (EndoFrost; Roeko, Langenau, Germany) were selected.
The time from the last radiation session had to be a minimum of 6 months. A further requirement was the non existence of periodontal pockets deeper than 4 mm. Teeth not able to be isolated with rubber dam were excluded. Patients under antibiotic treatment in the last 3 months could not be included in this clinical study.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The chemomechanical preparation employing reciprocating system in irradiated teeth complemented by final irrigation protocols with either ultrasonic or syringe and a needle demonstrated efficacy in reducing the endodontic contaminant contents.
- Secondary Outcome Measures
Name Time Method The use of intracanal medication with Ca(OH)2 should be performed in irradiated patients with infected root canals.